MARINOL (MARE-in-all) Capsules is part of a class of medications called cannabinoids. The active ingredient of MARINOL Capsules is man-made dronabinol (dro-NAB-in-all), also chemically known as tetrahydrocannabinol, or THC. THC is also a naturally occurring component of marijuana.
MARINOL Capsules Are Used:1
- To help manage loss of appetite associated with weight loss in patients with acquired immune deficiency syndrome (AIDS)
- For nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional treatment to relieve nausea and vomiting
MARINOL Capsules Were Shown to Be Effective in Clinical Trials:1
- At week 4 and 6, patients who took MARINOL Capsules for the treatment of AIDS-related anorexia associated with weight loss had a greater increase in appetite than those taking a placebo. Trends toward improved body weight and mood, and decreases in nausea were also seen.
- The antiemetic effect of MARINOL Capsules was greatest in patients receiving chemotherapy with MOPP* for Hodgkin’s and non-Hodgkin’s lymphoma.
*MOPP refers to a chemotherapy combination containing the following prescription drugs: Mustargen®, Oncovin®, procarbazine, and prednisone.2