answers to
frequently asked questions

Below are answers to some frequently asked questions about MARINOL Capsules.

Dronabinol, the active ingredient in MARINOL (dronabinol) capsules, is synthetic delta-9-tetrahydrocannabinol (THC). Delta-9-tetrahydrocannabinol is also a naturally occurring component of Cannabis sativa L. (marijuana). Drug tests are designed to detect delta-9-tetrahydrocannabinol (THC), among other chemicals.2
Yes, MARINOL Capsules is contraindicated in any patient who has a known sensitivity to MARINOL Capsules or any of its ingredients. It contains cannabinoid and sesame oil and should never be used by patients allergic to these substances.
A cannabinoid dose-related “high” (easy laughing, elation, and heightened awareness) has been reported by patients receiving MARINOL Capsules in both the antiemetic (24%) and the lower-dose appetite stimulant clinical trials (8%).1
Yes, caution is advised in prescribing MARINOL Capsules in elderly patients because they may be more sensitive to the neurological, psychoactive, and postural hypotensive effects of the drug.1 MARINOL Capsules should be used with caution in patients receiving concomitant therapy with sedatives, hypnotics, or other psychoactive drugs because of the potential for additive or synergistic CNS effects. For additional information, please see Full Prescribing Information.
MARINOL Capsules is abusable and controlled [Schedule III (CIII)] under the Controlled Substances Act. Both psychological and physiological dependence have been noted in healthy individuals receiving dronabinol, but addiction is uncommon and has been seen only after prolonged high-dose administration.1
Some insurance plans may require a prior authorization before MARINOL Capsules can be dispensed. Contact the specific healthcare plan to review product coverage and approval requirements.
Some insurance plans may have restrictions on the use of MARINOL Capsules. Contact the specific healthcare plan to review product coverage.
MARINOL Capsules should be stored in a cool place (46-59°F; 8-15°C) or in the refrigerator. The capsules should not be frozen. Heat or moisture may cause MARINOL Capsules to break down or stick together, so it’s advisable to keep this medicine away from heat and direct light, and potentially damp places such as the bathroom or near the kitchen sink.1

A prescription for controlled substances in Schedules III, IV, and V issued by a practitioner may be communicated either orally, in writing, or by facsimile to the pharmacist and may be refilled if so authorized on the prescription or by call-in.3

Refills: Schedule III and IV controlled substances may be refilled if authorized on the prescription. However, the prescription may be refilled only up to five times within 6 months after the date on which the prescription was issued. After five refills or after 6 months, whichever occurs first, a new prescription is required.3

Facsimile Prescriptions for Schedule III-V Substances: Prescriptions for Schedules III-V controlled substances may be transmitted by facsimile from the practitioner or an employee or agent of the individual practitioner to the dispensing pharmacy. The facsimile is considered to be equivalent to an original prescription.3

Telephone Authorization for Schedule III-V Prescriptions: A pharmacist may dispense a controlled substance listed in Schedule III, IV, or V pursuant to an oral prescription made by an individual practitioner and promptly reduced to writing by the pharmacist containing all information required for a valid prescription, except for the signature of the practitioner.3

Delivery of a Controlled Substance to Persons Outside the US: Controlled substances that are dispensed pursuant to a legitimate prescription may not be delivered or shipped to individuals in another country. Any such delivery or shipment is a prohibited export under the Controlled Substances Act.3

Yes, there is an approved generic version of MARINOL Capsules.